RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
mir-199a-1
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
NA
Target
KLOTHO;TLR4
Pathway
NA
PubMed ID
Title
Extracellular Vesicles from Albumin-Induced Tubular Epithelial Cells Promote the M1 Macrophage Phenotype by Targeting Klotho
Year
2019
Function
miR-199a-5p from hsa-stimulated human Kidney 2 (HK-2) cell-derived evs induces myocardial infarction (MI) polarization by targeting the klotho/Tlr4 pathway and further accelerates the progression of diabetic kidney disease (DKD).